NKL 22 , 98% , 是HDAC抑制剂
NKL 22, 98%, a HDAC inhibitor
分子式: C19H23N3O2
分子量: 325.40
纯度: 98%
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基本信息
安全信息
存储条件Freezer -20℃ | Symbol  |
Signal WordWarning | Hazard StatementsH315 H319 H335 |
Precautionary StatementsP280 P321 P261 P271 P319 P405 P501 P302+P352 P332+P317 P362+P364 P264+P265 P305+P351+P338 P337+P317 P304+P340 P403+P233 | |
化学和物理性质
产品描述
产品描述
NKL 22 is a HDAC inhibitor. The value of IC 50 is 78 uM NKL 22 increase frataxin protein concentrations NKL 22 inhibitors increase FXN mRNA in FRDA lymphocytes. HDAC inhibitors act directly on FXN. [1]
靶点（IC50 & Targe）
HDAC
参考文献
[1]. D Herman et al. Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia. Nat Chem Biol, 2006 Oct, 2(10):551-8.
