| 包装 | 库存 | 价格 | |
|---|---|---|---|
暂无数据 | |||
推荐产品
基本信息
英文别名4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide | |
中文别名4-氨基-N-(5,6-二甲氧基-4-嘧啶基)苯磺酰胺 | |
MDL编码MFCD00792890 | Reaxys-RN (Beilstein)625453 |
Merck Index14,8906 | EC No.219-504-9 |
安全信息
存储条件Store at 2-8℃ | Symbol  |
Signal WordWarning | Hazard StatementsH315 H319 H335 |
Precautionary StatementsP280 P321 P261 P271 P319 P405 P501 P302+P352 P332+P317 P362+P364 P264+P265 P305+P351+P338 P337+P317 P304+P340 P403+P233 | |
WGK Germany2 | RTECSDA9500000 |
TSCA0 | |
化学和物理性质
MP190-194 |
产品描述
一般描述
Chemical structure: sulfonamide
应用
Sulfadoxine is a sulfonamide antibiotic used in combination with pyrimethamine for the treatment or prevention of malaria. It is also used to treat various infections in livestock. Sulfadoxine and pyrimethamine is indicated for the treatment of Plasmodium falciparum malaria in patients where chloroquine resistance is suspected. It is used to study infections caused by Toxoplasma gondii and has been used to prevent infections after surgery during animal studies.
生化/生理作用
Sulfadoxine is a sulfonamide antibacterial that inhibits dihydropteroate synthase (DHPS), an enzyme that transforms 4-aminobenzoic acid (PABA) in the synthesis of dihydropteroic acid. This enzyme is also a component of the folate metabolic pathway and is upstream of dihydrofolate reductase (DHFR).
其他说明
Keep container tightly closed in a dry and well-ventilated place.Storage class (TRGS 510): Non Combustible Solids
