新污染物聚焦——环境中典型抗生素
时间: 2024-06-03
作者: 百灵威
分享:
抗生素是一类对多种或特定病原微生物具有强力抑制或杀灭作用的化合物。自1929年第一种抗生素-青霉素发现至今，科学家已经发现并研究合成了数万种抗生素，抗生素在人类医疗、畜牧和水产养殖等方面作出了巨大的贡献。
但抗生素的滥用现象严重，且其在机体内吸收有限。大量抗生素及其代谢物进入自然环境，诱导生物体产生抗生素抗性基因，对生态环境和人体健康造成威胁。
作为抗生素生产和使用大国，我国已将抗生素作为典型新污染物加强管控。
磺胺类、四环素类、喹诺酮类、大环内酯类和β-内酰胺类是中国消耗量较大的五大类抗生素。百灵威可供应近十类上百种抗生素标准物质，同时供应抗生素分析用氘代内标物以及配套试剂耗材。
磺胺类
标准品| 品名 | CAS | 货号 |
|---|---|---|
| Sulfacetamide, 99.5%, reference material 乙酰磺胺 | 144-80-9 | 999215 |
| Sulfachloropyridazine, 97%, reference material 磺胺氯哒嗪 | 80-32-0 | 367197 |
| Sulfadiazine, 99%, reference material 磺胺嘧啶 | 68-35-9 | 907349 |
| Sulfadimethoxine, 98%, reference material 磺胺地索辛 | 122-11-2 | 961285 |
| Sulfadoxine, 99%, reference material 磺胺多辛 | 2447-57-6 | 930666 |
| Sulfaguanidine, 99%, reference material 磺胺脒 | 57-67-0 | 913293 |
| Sulfamerazine, 98%, reference material 磺胺甲基嘧啶 | 127-79-7 | 236883 |
| Sulfameter, 98%, reference material 磺胺对甲氧嘧啶 | 651-06-9 | 972921 |
| Sulfamethazine, 99%, reference material 磺胺二甲基嘧啶 | 57-68-1 | 959430 |
| Sulfamethizole, 98%, reference material 磺胺甲二唑 | 144-82-1 | 315878 |
| Sulfamethoxazole, 99.5%, reference material 磺胺甲基噁唑 | 723-46-6 | 926830 |
| Sulfamethoxypyridazine, 99%, reference material 磺胺甲氧哒嗪 | 80-35-3 | 974568 |
| Sulfamonomethoxine, 97%, reference material 磺胺间甲氧嘧啶 | 1220-83-3 | 908544 |
| Sulfanilamide, 99.5%, reference material 磺胺 | 63-74-1 | 244744 |
| Sulfaphenazole, 99%, reference material 磺胺苯吡唑 | 526-08-9 | 921240 |
| Sulfapyridine, 99.5%, reference material 磺胺吡啶 | 144-83-2 | 949456 |
| Sulfaquinoxaline, 95%, reference material 磺胺喹噁啉 | 59-40-5 | 291027 |
| Sulfathiazole, 99%, reference material 磺胺噻唑 | 72-14-0 | 989129 |
| Sulfisoxazole, 99%, reference material 磺胺异噁唑 | 127-69-5 | 961194 |
| Trimethoprim, 99%, reference material 甲氧苄啶 | 738-70-5 | 983158 |
| 品名 | CAS | 货号 |
|---|---|---|
| Sulfadiazine-D4, 98%, reference material 磺胺嘧啶-D4 | 1020719-78-1 | 429570 |
| Sulfadimethoxine-D6, 98%, reference material 磺胺二甲氧嘧啶-D6 | 73068-02-7 | 796801 |
| Sulfadoxine-d3, 98%, reference material 磺胺多辛-d3 | 1262770-70-6 | 796802 |
| Sulfapyridine-D4, 98%, reference material 磺胺吡啶-D4 | 1189863-86-2 | 837027 |
| Sulfamethazine-d4, 98%, reference material 磺胺二甲嘧啶-d4 | 1020719-82-7 | 989590 |
| Sulfadimethoxine-D4, 98%, reference material 磺胺二甲氧基嘧啶-D4 | 1020719-80-5 | 1750754 |
| Sulfamerazine D4, 98%, reference material 磺胺甲基嘧啶-D4 | 1020719-84-9 | 1888784 |
| Sulfathiazole-d4, 98%, reference material 磺胺噻唑-d4 | 1020719-89-4 | 1888790 |
| Sulfamonomethoxine-d4, 98%, reference material 磺胺间甲氧嘧啶-d4 | 1286538-12-2 | 2063061 |
| Sulfaquinoxaline-D4, 98%, reference material 磺胺喹恶啉-D4 | 1329652-02-9 | 9065806 |
| Sulfamethoxazole-D4, 98%, 98 atom%D 磺胺甲恶唑-D4 | 1020719-86-1 | 929793 |
| Sulfadoxine-d4, 98%, reference material 磺胺邻二甲氧嘧啶-d4 | 1330266-05-1 | 2063059 |
喹诺酮类
标准品| 品名 | CAS | 货号 |
|---|---|---|
| Cinoxacin, 98%, reference material 西诺沙星 | 28657-80-9 | 999921 |
| Ciprofloxacin hydrochloride monohydrate, 99%, reference material 环丙沙星盐酸盐一水合物 | 86393-32-0 | 923388 |
| Ciprofloxacin hydrochloride, 98%, reference material 环丙沙星盐酸盐 | 93107-08-5 | 1211702 |
| Ciprofloxacin lactate, 98%, reference material 乳酸环丙沙星 | 97867-33-9 | 243199 |
| Ciprofloxacin, 98%, reference material 环丙沙星 | 85721-33-1 | 986785 |
| Danofloxacin mesylate, 98%, reference material 甲磺酸达氟沙星 | 119478-55-6 | 977675 |
| Difloxacin hydrochloride, 98%, reference material 盐酸二氟沙星 | 91296-86-5 | 239053 |
| Enoxacin sesquihydrate, 99.5%, reference material 依诺沙星 倍半水合物 | 84294-96-2 | 927984 |
| Enoxacin, 99%, reference material 依诺沙星 | 74011-58-8 | 972241 |
| Enrofloxacin, 99.5%, reference material 恩氟沙星 | 93106-60-6 | 979347 |
| Fleroxacin, 99.5%, reference material 氟罗沙星 | 79660-72-3 | 914617 |
| Gatifloxacin, 99%, reference material 加替沙星 | 112811-59-3 | 980522 |
| Lomefloxacin hydrochloride, 99%, reference material 洛美沙星盐酸盐 | 98079-52-8 | 932377 |
| Marbofloxacin, 99%, reference material 麻保沙星 | 115550-35-1 | 999377 |
| Moxifloxacin hydrochloride, 98%, reference material 盐酸莫西沙星 | 186826-86-8 | 217292 |
| Moxifloxacin, 98%, reference material 莫西沙星 | 151096-09-2 | 960326 |
| Norfloxacin, 98%, reference material 诺氟沙星 | 70458-96-7 | 959694 |
| Ofloxacin, 99.5%, reference material 氧氟沙星 | 82419-36-1 | 916029 |
| Orbifloxacin, 99.5%, reference material 奥比沙星 | 113617-63-3 | 962887 |
| Oxolinic acid, 98%, reference material 噁喹酸 | 14698-29-4 | 949420 |
| Pefloxacin mesylate dihydrate, 98%, reference material 甲磺酸培氟沙星二水合物 | 149676-40-4 | 977438 |
| Sarafloxacin hydrochloride, 98%, reference material 盐酸沙拉沙星 | 91296-87-6 | 924297 |
| Sparfloxacin, 99%, reference material 司帕沙星 | 110871-86-8 | 500621 |
| 品名 | CAS | 货号 |
|---|---|---|
| Ciprofloxacin-d8 Hydrochloride, 98%, reference material 盐酸环丙沙星-D8 | 1216659-54-9 | 796796 |
| Norfloxacin-d5, 98%, reference material 诺氟沙星-d5 | 1015856-57-1 | 796946 |
| Enrofloxacin-d5, 98%, reference material 恩诺沙星-D5 | 1173021-92-5 | 813423 |
| Ciprofloxacin-d8, 98%, reference material 环丙沙星-d8 | 1130050-35-9 | 1445520 |
| Pefloxacin-D5, 98%, reference material 培氟沙星-D5 | 1228182-51-1 | 9000827 |
四环素类
标准品| 品名 | CAS | 货号 |
|---|---|---|
| Doxycycline hyclate, 99%, reference material 盐酸强力霉素 | 24390-14-5 | 933030 |
| Doxycycline hydrochloride, 88%, reference material 盐酸多西环素 | 10592-13-9 | 608407 |
| Doxycycline, 98%, reference material 强力霉素 | 564-25-0 | 101324 |
| Methacycline hydrochloride, 98%, reference material 甲烯土霉素盐酸盐 | 3963-95-9 | 917064 |
| Oxytetracycline hydrochloride, 97%, reference material 盐酸土霉素 | 2058-46-0 | 933862 |
| Oxytetracycline, 97%, reference material 土霉素 | 79-57-2 | 910069 |
大环内酯类
标准品| 品名 | CAS | 货号 |
|---|---|---|
| Azithromycin, 98%, reference material 阿奇霉素 | 83905-01-5 | 963892 |
| Doramectin, 98%, reference material 多拉克汀 | 117704-25-3 | 921184 |
| Ivermectin, 96%, reference material 伊维菌素 | 70288-86-7 | 933126 |
| Roxithromycin, 98%, reference material 罗红霉素 | 80214-83-1 | 982370 |
| Spiramycin, 92%, reference material 螺旋霉素 | 8025-81-8 | 927982 |
| Tilmicosin, 90%, reference material 替米考星 | 108050-54-0 | 574018 |
| Tylosin tartrate, 98%, reference material 酒石酸泰洛星 | 74610-55-2 | 530782 |
β-内酰胺类
标准品| 品名 | CAS | 货号 |
|---|---|---|
| Amoxicillin, 98%, reference material 阿莫西林三水酸 | 26787-78-0 | 919754 |
| Ampicillin, 99%, reference material 氨苄西林 | 69-53-4 | 945452 |
| Cefdinir, 98%, reference material 头孢地尼 | 91832-40-5 | 599991 |
| Cephradine, 90%, reference material 头孢拉定 | 38821-53-3 | 414143 |
| Oxacillin sodium salt monohydrate, 99.5%, reference material 苯唑西林钠盐一水合物 | 7240-38-2 | 332056 |
其他典型抗生素
| 品名 | CAS | 货号 |
|---|---|---|
| Ampicillin trihydrate, 99%, reference material 氨苄西林三水合物 | 7177-48-2 | 948845 |
| Chloramphenicol, 99.5%, reference material 氯霉素 | 56-75-7 | 912378 |
| Flubendazole, 98.5%, reference material 氟苯达唑 | 31430-15-6 | 129961 |
| Hygromycin B, 90%, reference material 潮霉素B | 31282-04-9 | 961157 |
| Oxfendazole, 99%, reference material 奥芬达唑 | 53716-50-0 | 978821 |
| Streptomycin sulfate, 98%, reference material 硫酸链霉素 | 3810-74-0 | 991566 |
| Thiamphenicol, 99%, reference material 甲砜霉素 | 15318-45-3 | 950887 |
| Tobramycin, 96%, reference material 妥布霉素 | 32986-56-4 | 984009 |
抗生素分析常用试剂
| 品名 | CAS | 货号 |
|---|---|---|
| Methanol, 99.9%, LC-MS 甲醇 | 67-56-1 | 958209 危化品 |
| Acetonitrile, 99.9%, LC-MS 乙腈 | 75-05-8 | 912457 危化品 |
| Formic acid, 98%, for LC-MS 甲酸 | 64-18-6 | 942988 危化品 |
| Ethylenediaminetetraacetic acid disodium salt dihydrate, 99%, for analysis 乙二胺四乙酸二钠盐二水合物 | 6381-92-6 | 976151 |
| Ammonium hydroxide, for analysis, 25-28% 氢氧化铵 | 1336-21-6 | 921637 危化品 |
| Citric acid, 98%, anhydrous 柠檬酸 | 77-92-9 | 947677 |
| Sodium phosphate dibasic, 99%, ACS reagent 磷酸氢二钠 | 7558-79-4 | 947717 |
| Sodium dihydrogen phosphate, 99% 磷酸二氢钠 | 7558-80-7 | 938365 |
| Sodium hydroxide, 96%, for analysis, granular 氢氧化钠 | 1310-73-2 | 970488 危化品 |
抗生素分析常用耗材
| 品名 | CAS | 货号 |
|---|---|---|
| Delishell C18 HPLC column, 100×4.6 mm 2.6μm C18核壳液相色谱柱 | / | 9337268 |
| HLB SPE Cartridges, bed wt. 200 mg, volume 6 ml, 30 pcs/pack HLB 固相萃取小柱 | / | 948068 |
| MAX SPE Cartridges, bed wt. 150 mg, volume 6 ml, 30 pcs/pack MAX 固相萃取小柱 | / | 994507 |
| Microporous membrane filters, CA, non-sterile, white, Ф47, 0.45μm, 50 pcs/pack 微孔滤膜 | / | 986357 |
| MCE syringe filter, non-sterile, 25 mm, 0.22 µm, 100 pcs/pack 水系混合纤维素针式过滤器 | / | 9217640 |
| Short screw thread vials, 2ml, 9mm, 11.6×32mm, with marking spot, amber, wide opening 短螺纹样品瓶 | / | 902590 |
| Short screw thread vial caps and septa, 9 mm blue pp cap, centre hole 6 mm, pre-slit blue PTFE/white silicone septum 短螺纹样品瓶组合盖垫 | / | 993144 |
| Syringe filter, PTFE membrane (hydrophillic), non-sterile, 13mm, 0.45µm, 200 pcs/pack 针头式过滤器 | / | 2123704 |
| Single-channel mechanical pipettor, Volume range: 50 - 200 μL, Increment: 1.0 μL 单道手动可调移液器 | / | 997681 |
| Pipette tips, 200 μL, yellow, low Retention, 1000 tips/pack 移液器吸头 | / | 1438546 |
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