3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee),3-[[3,5-双(三氟甲基)苯基]氨基]-4-[(1S,2S)-2-(1-吡咯烷基)环己基]氨基]-3-环丁烯-1,2-二酮 , 98%, (99% ee)
3-[[3,5-双(三氟甲基)苯基]氨基]-4-[(1S,2S)-2-(1-吡咯烷基)环己基]氨基]-3-环丁烯-1,2-二酮 , 98%, (99% ee)
3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee)
品牌: Strem
产品编号: 07-5611
分子式: C22H23F6N3O2
分子量: 475.40
纯度: 98%, (99% ee)
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Technical Notes:

1.Mannich Reaction: The asymmetric addition of the present HWE reagents to N-ca rbamoyl imines

generated in situ was achieved. The corresponding Mannich adducts can be further transformed to aza- MBH type products in good to excellent enantioselectivities.

References:

1. Chem. Sci., 2011, 2, 1918-1921.

参考文献