免疫诊断技术及相关原辅料
时间: 2024-09-11
作者: 百灵威
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免疫诊断是以免疫学为基础，利用抗原抗体间的特异性免疫反应来测定免疫状态、检测各种疾病的诊断方法。
免疫诊断包括放射免疫、酶联免疫、层析免疫分析、胶乳免疫比浊和化学发光等。酶联免疫试剂具有成本低、可大规模操作等特点；而化学发光试剂具有灵敏、快速、稳定、选择性强、重现性好、易于操作、方法灵活多样的优点。广泛应用于医院、血站、体检中心，用于肝炎检测、性病检测、肿瘤检测、孕检等。
百灵威提供酶联免疫、层析免疫、胶乳免疫比浊和化学发光相关的试剂。
1、胶乳免疫比浊（LETIA)2、层析免疫分析（LFIA)
3、酶联免疫吸附（ELISA)
4、化学发光免疫（CLIA)
5、通用试剂
1、胶乳免疫比浊（LETIA)
氨基胶乳微球
| 品名 | CAS | 货号 |
|---|---|---|
| Amino polystyrene microspheres, 0.2 μm, 2.5% (w/v) suspended in deionized water 氨基聚苯乙烯微球 | 9003-53-6 | 1927286 |
| Amino polystyrene microspheres, 2 μm, 2.5% (w/v) suspended in deionized water 氨基聚苯乙烯微球 | 9003-53-6 | 921972 |
| 1,3-BIS(3-IODOPHENYL)-2-THIOUREA 1,3-BIS(3-IODOPHENYL)-2-THIOUREA | 195531-92-1 | S875295 |
| Amino polystyrene microspheres, 7 μm, 2.5% (w/v) suspended in 50% ethanol solution 氨基聚苯乙烯微球 | 9003-53-6 | 987272 |
羧基胶乳微球
| 品名 | CAS | 货号 |
|---|---|---|
| Carboxyl polystyrene microspheres, 0.2 μm, 2.5%（w/v）suspended in deionized water 羧基聚苯乙烯微球 | 9003-53-6 | 937524 |
| Carboxyl polystyrene microspheres, 2-3 μm, 2.5% (w/v) suspended in deionized water 羧基聚苯乙烯微球 | 9003-53-6 | 1927287 |
| Carboxyl polystyrene microspheres, 3 μm, 2.5% (w/v) suspended in deionized water 羧基聚苯乙烯微球 | 9003-53-6 | 996252 |
其他胶乳微球
| 品名 | CAS | 货号 |
|---|---|---|
| Polystyrene microspheres, 0.09 μm, 2.5%（w/v）suspended in deionized water 聚苯乙烯微球 | 9003-53-6 | 951688 |
| Polystyrene microspheres, 0.1 μm, 2.5% (w/v) suspended in deionized water 聚苯乙烯微球 | 9003-53-6 | 930141 |
| Polystyrene microspheres, 0.2 μm, 2.5%（w/v）suspended in deionized water 聚苯乙烯微球 | 9003-53-6 | 945642 |
| Polystyrene microspheres, 0.3 μm, 2.5% (w/v) suspended in deionized water 聚苯乙烯微球 | 9003-53-6 | 917425 |
| Polystyrene microspheres, 0.4 μm, 2.5%（w/v）suspended in deionized water 聚苯乙烯微球 | 9003-53-6 | 909904 |
| Polystyrene microspheres, 0.6-1.0 μm, 2.5% (w/v) suspended in deionized water 聚苯乙烯微球 | 9003-53-6 | 934330 |
| Polystyrene microspheres, 1 μm, 2.5% (w/v) suspended in deionized water 聚苯乙烯微球 | 9003-53-6 | 909275 |
| Polystyrene microspheres, 2 μm, 2.5% (w/v) suspended in deionized water 聚苯乙烯微球 | 9003-53-6 | 980959 |
| Polystyrene microspheres, 5 μm, 2.5% (w/v) suspended in deionized water 聚苯乙烯微球 | 9003-53-6 | 1927285 |
| Polystyrene microspheres, 6 μm, 2.5% (w/v) suspended in 50% ethanol solution 聚苯乙烯微球 | 9003-53-6 | 980070 |
| Polystyrene microspheres, 10 μm, 2.5% (w/v) suspended in 50% ethanol solution 聚苯乙烯微球 | 9003-53-6 | 945308 |
| Polystyrene microspheres, 11 μm, 2.5% (w/v) suspended in 50% ethanol solution 聚苯乙烯微球 | 9003-53-6 | 987153 |
| Polystyrene microspheres, 20 μm, 2.5% (w/v)suspended in 50% ethanol solution 聚苯乙烯微球 | 9003-53-6 | 925149 |
交联剂
| 品名 | CAS | 货号 |
|---|---|---|
| N-Hydroxysuccinimide, 98% N-羟基琥珀酰亚胺 | 6066-82-6 | 117997 |
| N-Hydroxysulfosuccinimide sodium salt, 98% N-羟基磺酰基琥珀酰亚胺钠盐 | 106627-54-7 | 183144 |
| N-hydroxysulfosuccinimide sodium salt, 98%, White to off-white solid N-羟基磺酰基琥珀酰亚胺钠盐 | 106627-54-7 | 904379 |
| N-Succinimidyl-4-(maleimidomethyl)cyclohexane-1-carboxylate, 99% N-琥珀酰亚胺基-4-(马来酰亚胺基甲基)环己烷-1-羧酸酯 | 64987-85-5 | 467057 |
| Sulfo-SMCC sodium, 95% 磺基-SMCC钠盐 | 92921-24-9 | 253343 |
| (+)-Biotin-N-hydroxysuccinimide ester, 99% (+)-生物素-N-羟基琥珀酰亚胺酯 | 35013-72-0 | 454043 |
| Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester), 95% 乙二醇 -双(琥珀酸 N-羟基琥珀酰亚胺酯) | 70539-42-3 | 359030 |
2、层析免疫分析（LFIA)
胶体金免疫层析技术
| 品名 | CAS | 货号 |
|---|---|---|
| Gold(III) chloride hydrate, reagent grade, Au ≥ 47.5% 四氯金(III)酸水合物 | 27988-77-8 | 930848 |
| Gold(III) chloride trihydrate, 49.0% Au 四氯化金(III)酸三水合物 | 16961-25-4 | 189892 |
| L-Ascorbic acid, 99% 抗坏血酸 | 50-81-7 | 231406 |
| Sodium citrate, 99%, reagent grade, anhydrous 柠檬酸钠 | 68-04-2 | 439754 |
| Tannic Acid 鞣酸;单宁酸;丹宁酸;没食子鞣酸 | 1401-55-4 | T006560 |
免疫荧光层析
检测标记物
| 品名 | CAS | 货号 |
|---|---|---|
| Green fluorescent microspheres, 2 μm, 1% (w/v) suspended in deionized water 绿色荧光微球 | / | 1927297 |
| Green fluorescent microspheres, 3 μm, 1% (w/v) suspended in deionized water 绿色荧光微球 | / | 958512 |
| Green fluorescent microspheres, 5 μm, 1% (w/v) suspended in deionized water 绿色荧光微球 | / | 992917 |
| Orange fluorescent microspheres, 4 μm, 1% (w/v) suspended in deionized water 橙色荧光微球 | / | 1927296 |
| Red fluorescent microspheres, 1 μm, 1% (w/v) suspended in deionized water 红色荧光微球 | / | 1927295 |
荧光染料
| 品名 | CAS | 货号 |
|---|---|---|
| Fluorescein 5(6)-isothiocyanate, 95%, for fluorescence, mixture of 5- and 6- isomers 5(6)-异硫氰酸荧光素 | 27072-45-3 | 194222 |
| Fluorescein isothiocyanate isomer I, 90% 异硫氰酸荧光素异构体I | 3326-32-7 | 152449 |
| Fluorescein isothiocyanate isomer I, 95% 异硫氰酸荧光素异构体 I | 3326-32-7 | 255493 |
| Rhodamine B, 96% 罗丹明B | 81-88-9 | 603231 |
3、酶联免疫吸附（ELISA)
检测标记物
| 品名 | CAS | 货号 |
|---|---|---|
| Peroxidase, from horseradish, 200 units/mg 过氧化物酶 | 9003-99-0 | 202884 |
| Alkaline phosphatase, ≥2500 U/mg protein 碱性磷酸酯酶 | 9001-78-9 | 933347 |
酶底物
| 品名 | CAS | 货号 |
|---|---|---|
| p-Nitrophenyl phosphate disodium salt hexahydrate, 98% 对硝基苯磷酸二钠盐六水合物 | 333338-18-4 | 930173 |
| 3,3',5,5'-Tetramethylbenzidine, 99%, reagent grade 3,3',5,5'-四甲基联苯胺 | 54827-17-7 | 184947 |
| Catechol, 99% 邻苯二酚 | 120-80-9 | 359694 危化品 |
4、化学发光免疫（CLIA)
直接化学发光
发光标记物
| 品名 | CAS | 货号 |
|---|---|---|
| 2',6'-Dimethyl-4'-(N-succinimidyloxycarbonyl)phenyl-10-methyl-acridinium-9-carboxylate-1-propanesulfonate inner salt, 95% 吖啶酯 | 194357-64-7 | 1188905 |
| DMAE-NHS, 98% 吖啶酯 | 115853-74-2 | 1188904 |
| NSP-SA-NHS, 98% NSP-SA-NHS吖啶盐 | 199293-83-9 | 1440680 |
| Acridine ester ME-DMAE-NHS, 98% 吖啶酯ME-DMAE-NHS | 115853-73-1 | 9372456 |
| NSP-SA, 98% 吖啶酸丙磺酸盐 | 211106-69-3 | 996682 |
酶促化学发光免疫分析
酶
| 品名 | CAS | 货号 |
|---|---|---|
| Peroxidase, from horseradish, 200 units/mg 过氧化物酶 | 9003-99-0 | 202884 |
发光底物
| 品名 | CAS | 货号 |
|---|---|---|
| CDP-Star, 98% CDP-Star 化学发光底物 | 160081-62-9 | 566933 |
| APS-5, 98% APS-5 | 193884-53-6 | 2327433 |
| APS-5 01 APS-5底物液01 | / | 9372452 |
| APS-5 02 APS-5底物液02 | / | 9372453 |
| APS-5 03 APS-5底物液03 | / | 9372454 |
| APS-5 04 APS-5底物液04 | / | 9372455 |
| AMPPD, 97% 3-(2'-螺旋金刚烷)-4-甲氧基-4-(3;3-(2-螺旋金刚烷)-4-甲氧基-4-(3-磷氧酰)-苯基-1,2-二氧环乙烷 | 122341-56-4 | 922576 |
| AMPPD AMPPD底物液 | / | 920549 |
| Luminol, 98% 鲁米诺 | 521-31-3 | 328061 |
| N-(4-Aminobutyl)-N-ethylisoluminol, 97% N-(4-氨丁基)-N-乙基异鲁米诺 | 66612-29-1 | 482541 |
化学发光增强剂
| 品名 | CAS | 货号 |
|---|---|---|
| Sodium tetraphenylborate, 99%, for analysis 四苯基硼酸钠 | 143-66-8 | 963240 |
| Hydroquinone, 98%, AR 对苯二酚 | 123-31-9 | 902660 危化品 |
| 4-Iodophenol 4-碘苯酚 | 540-38-5 | OR5400 危化品 |
| 4-Hydroxybiphenyl, 99% 4-羟基联苯 | 92-69-3 | 225018 |
| 2-Amino-2-methyl-1-propanol, 95% 2-氨基-2-甲基-1-丙醇 | 124-68-5 | 386206 |
| 3-(Phenothiazin-10-yl)propane-1-sulfonate, 97% 3-(-10-吩噻嗪基)丙烷-1-磺酸钠 | 101199-38-6 | 271992 |
电化学发光
| 品名 | CAS | 货号 |
|---|---|---|
| 4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid, 99% 4-(2-羟乙基)-1-哌嗪丙磺酸 | 16052-06-5 | 374184 |
| Tripropylamine, 98% 三正丙胺 | 102-69-2 | 145253 危化品 |
| Tris(2,2'-bipyridyl)ruthenium(II)chloride hexahydrate, 98% 三(2,2’-联吡啶基)氯化钌(II)六水合物 | 50525-27-4 | 102033 |
通用试剂
固相载体——磁珠
| 品名 | CAS | 货号 |
|---|---|---|
| Amino Fe3O4 magnetic beads , 0.1 - 0.2 μm, 0.5% (w/v) suspended in PBS buffer solution 氨基四氧化三铁磁珠 | 1317-61-9 | 1924547 |
| Amino Fe3O4 magnetic beads, 0.2 - 0.3 μm, 0.5% (w/v) suspended in PBS buffer solution 氨基四氧化三铁磁珠 | 1317-61-9 | 914411 |
| Amino polystyrene magnetic beads, 1 - 2 μm, 0.5% (w/v) suspended in PBS buffer solution 氨基聚苯乙烯磁珠 | / | 1924551 |
| Amino silica magnetic beads, SLC, 1 - 2 μm, 1% (w/v) suspended in PBS buffer solution 氨基二氧化硅磁珠 | 14808-60-7 | 952697 |
| Amino silica magnetic beads, SLE, 1 - 2 μm, 1% (w/v) suspended in PBS buffer solution 氨基二氧化硅磁珠 | 14808-60-7 | 1924554 |
| Carboxylated Fe3O4 magnetic beads, 0.1 - 0.2 μm, 0.5% (w/v) suspended in PBS buffer solution 羧基四氧化三铁磁珠 | 1317-61-9 | 1924549 |
| Carboxylated Fe3O4 magnetic beads, 0.2 - 0.3 μm, 0.5% (w/v) suspended in PBS buffer solution 羧基四氧化三铁磁珠 | 1317-61-9 | 943117 |
| Carboxylated polystyrene magnetic beads, 1 - 2 μm, 0.5% (w/v) suspended in PBS buffer solution 羧基聚苯乙烯磁珠 | / | 1924552 |
| Carboxylated silica magnetic beads, SLC, 1 - 2 μm, 1% (w/v) suspended in PBS buffer solution 羧基二氧化硅磁珠 | 14808-60-7 | 982842 |
| Carboxylated silica magnetic beads, SLE, 1 - 2 μm, 1% (w/v) suspended in PBS buffer solution 羧基二氧化硅磁珠 | 14808-60-7 | 1924555 |
| Hydroxy Fe3O4 magnetic beads, 0.1 - 0.2 μm, 0.5% (w/v) suspended in PBS buffer solution 羟基四氧化三铁磁珠 | 1317-61-9 | 1924550 |
| Hydroxy Fe3O4 magnetic beads, 0. 2- 0.3 μm, 0.5% (w/v) suspended in PBS buffer solution 羟基四氧化三铁磁珠 | 1317-61-9 | 943871 |
| Silicon hydroxyl group polystyrene magnetic beads, 1 - 2 μm, 0.5% (w/v) suspended in PBS buffer solution 硅羟基聚苯乙烯磁珠 | / | 1924553 |
| Hydroxyl silica magnetic beads, SLC, 1 - 2 μm, 1% (w/v) suspended in PBS buffer solution 羟基二氧化硅磁珠 | 14808-60-7 | 975134 |
| Hydroxyl silica magnetic beads, SLE, 1 - 2 μm, 1% (w/v) suspended in PBS buffer solution 羟基二氧化硅磁珠 | 14808-60-7 | 1924556 |
| Iron oxide(II,III), magnetic nanoparticles solution, amino-polyacrylamide functionalized, particle size:20-50 nm avg., 5 mg/ml in H2O 四氧化三铁磁性纳米粒子溶液 | 1317-61-9 | 9020742 |
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